Acrodisc® Syringe Filters with Supor® Membrane

High Flow Rates with Low Protein Binding

• Superior flow rates and higher throughputs than competitive devices.
• Low protein binding to minimize sample loss.
• Pre-sterilized products are sterilized by gamma irradiation to eliminate potential contamination by EtO residuals.
• A range of sizes (13 to 37 mm) accommodates sample volumes from < 10 to 150 mL.
• Acrodisc PF and Serum Acrodisc syringe filters feature built-in prefilter for increased throughput of difficult-to-filter liquids.
• Reduces mycoplasma with the use of 0.1 μm pore size.

• 0.1 and 0.2 μm pore sizes provide sterilization of small volumes of buffers, culture media, and additives.
• Acrodisc PF and Serum Acrodisc syringe filters are ideal for clarification/sterilization of viscous or particulate-laden solutions.
• Use larger pore size filters for prefiltration and particulate removal.

Materials of Construction

Filter Media: Supor membrane [hydrophilic polyethersulfone (PES)]
Serum Acrodisc Prefilter Media: Binder-free borosilicate glass
Acrodisc Housing:
  13 mm: Polypropylene
  25 and 32 mm: Modified acrylic
  37 mm: Polypropylene
Serum Acrodisc Housing: ABS 

Pore Size

0.1, 0.2, 0.45, 0.8, 1.2, and 5 µm

Effective Filtration Area

13 mm: 1.0 cm²
25 mm: 2.8 cm²
32 mm: 5.8 cm²
37 mm: 7.5 cm²

Inlet/Outlet Connections

Female luer lock inlet, male slip luer outlet

Typical Hold-Up Volume

(with air purge)
13 mm: < 28 µL
25 mm: < 70 µL
32 and 37 mm: <100 µL

Maximum Operating Temperature

55 °C (131 °F)

Maximum Operating Pressure

5.2 bar (520 kPa, 75 psi)

Typical Water Flow Rate

mL/min at 3.1 bar (310 kPa, 45 psi)
0.1 μm, 25 mm: 35
0.1 μm, 32 mm: 100
0.2 μm, 13 mm: 22
0.2 μm, 25 mm: 175
0.2 μm, 32 mm: 490
0.45 μm, 13 mm: 35
0.45 μm, 25 mm: 300
0.45 μm, 32 mm: 700
0.8 μm, 13 mm: 150
0.8 μm, 25 mm: 700
0.8/0.2 μm, 25 mm: 145
0.8/0.2 μm, 32 mm: 440
1.2 μm, 32 mm: 1700
5 μm, 32 mm: 1750
GF/0.2 μm, 37 mm (Serum
Acrodisc Filter): 425

Endotoxin Level

< 0.25 EU/mL using Limulus Amoebocyte Lysate (LAL) test

Biological Safety

Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88>

Sterilization

Sterilized by gamma irradiation and individually blister packaged. All bulk packages provided non-sterile including PN 4504, 4506, 4508, 4509, 4655, 4653, 4659, 4660, 4661, 4662, 4668, and 4692.

• AcroCap Positive Pressure Devices
• AcroPak 20 Filters with with Supor Membrane
• AcroPak 200 Capsules with Supor Membrane
• AcroPak 500, 1000, and 1500 Capsules with Supor Membrane
• Supor Membrane Disc Filters
• VacuCap Vacuum Filtration Devices

Built-In Prefilter Enhances Throughput of Viscous, Particulate-Laden, or Proteinaceous Solutions

Acrodisc and Acrodisc PF syringe filters with 0.2 μm Supor membrane were challenged with bovine serum or a bacterial culture (107 cfu/mL) at a constant pressure of 1.4 bar (140 kPa, 20 psi).

Part Number	Description	Pkg	Price	Qty
Acrodisc Syringe Filters with Supor Membrane, Sterile
4602	0.2 µm, 13 mm	75/pkg	151.51
4604	0.45 µm, 13 mm	75/pkg	159.09
4608	0.8 µm, 13 mm	75/pkg	154.33
4611	0.1 µm, 25 mm	50/pkg	119.25
4612	0.2 µm, 25 mm	50/pkg	119.25
4614	0.45 µm, 25 mm	50/pkg	119.25
4618	0.8 µm, 25 mm	50/pkg	119.25
4651	0.1 µm, 32 mm	50/pkg	140.30
4652	0.2 µm, 32 mm	50/pkg	140.30
4654	0.45 µm, 32 mm	50/pkg	140.30
4656	1.2 µm, 32 mm	50/pkg	140.30
4650	5 µm, 32 mm	50/pkg	140.30
Acrodisc PF Syringe Filters with Supor Membrane, Sterile
4187	0.8/0.2 µm, 25 mm	50/pkg	140.17
4658	0.8/0.2 µm, 32 mm	50/pkg	168.34
Serum Acrodisc Syringe Filter with Supor Membrane, Sterile
4525	GF/0.2 µm, 37 mm	20/pkg	107.86
Acrodisc Syringe Filters with Supor Membrane, Non-Sterile Bulk Packaging
4692	0.2 µm, 13 mm	1000/pkg	1,245.40
4668	0.1 µm, 25 mm	1000/pkg	1,627.25
4506	0.2 µm, 25 mm	1000/pkg	1,632.80
4504	0.8/0.2 µm, 25 mm	1000/pkg	2,210.32
4508	0.45 µm, 25 mm	1000/pkg	1,632.80
4509	0.8 µm, 25 mm	1000/pkg	1,640.81
4655	0.2 µm, 32 mm	1000/pkg	2,021.67
4659	0.8/0.2 µm, 32 mm	1000/pkg	1,842.55
4653	0.45 µm, 32 mm	1000/pkg	1,982.67
4661	1.2/0.45 µm, 32 mm	1000/pkg	2,160.04
4660	1.2 µm, 32 mm	1000/pkg	2,021.67
4662	5 µm, 32 mm	1000/pkg	2,021.67

Contact Customer Service at 800-521-1520 for possible lead-time and ship date.