AcroPak™ 20 Filters & AcroPak 200 Capsule with Fluorodyne® II Membrane

Efficient Processing of Liquid
Volumes Typically Up To 20 L

• Fluorodyne II membrane is compatible with aqueous and many organic solvents
• AcroPak 20 filters are designed to add convenience to small- and medium-volume filtrations
• AcroPak 200 Fluorodyne II capsules provide fast processing of clean batches
• Double layer sterilizing membrane enhances reliability
• Upstream air vent prevents vapor lock
• Manufactured without the use of adhesives to minimize extractables
• Pre-sterilized by gamma irradiation

• Sterile filtration of media and buffers
• Point-of-use filtration for lab water
• Suitable for viscous, particulate solutions and serum containing media
• Applicable for many fluids containing dilute proteins or preservatives
• Scalable

Materials of Construction

• Filter Media: Fluorodyne II membrane (hydrophilic PVDF)
• Housing, Vent Plug: Polypropylene
• Sealing Technology: Thermal bonding
• Filling Bell: Polycarbonate

Pore Size

• 0.1 and 0.2 μm

Effective Filtration Area

• 20 and 200 cm²

Dimensions (Nominal)

• AcroPak 20 Filters
     Housing Length: 8.3 cm (3.3 in.)
     Housing Diameter: 6.7 cm (2.7 in.)
• AcroPak 200 Capsule
     Overall Length: 10.5 cm (4.1 in.)
     Housing Diameter Without Vent: 5.3 cm (2.1 in.)
     Housing Diameter With Vent: 6.7 cm (2.6 in.)

Inlet/Outlet Connections

• 6.4 - 12.7 mm (1/4 - 1/2 in.) diameter stepped hose barb with female luer slip interior and filling bell outlet

Maximum Operating Temperature and Pressure

• 60 °C (140 °F) at 1.0 bar (100 kPa, 15 psi)
• 4.1 bar (410 kPa, 60 psi) at 21 - 24 °C (70 - 75 °F)

Recommended Integrity Test Minimum Bubble Point – Water

• 0.2 μm Fluorodyne II membrane: 3.2 bar (320 kPa, 46 psi)

60% IPA/40% H2O (v:v)

• 0.1 μm Fluorodyne II membrane: 1.8 bar (180 kPa, 26 psi)

Typical Water Flow Rate mL/min at 0.1 bar (10 kPa) [mL/min/psi]

• AcroPak 20 Filters
     0.1 μm Fluorodyne II Membrane: 13 (9)
     0.2 μm Fluorodyne II Membrane: 26 (18)
• AcroPak 200 Capsule
     0.2 μm Fluorodyne II Membrane: 240 (170)

Typical Hold-Up Volume (with air purge)

• AcroPak 20 Filters < 2.5 mL
• AcroPak 200 Capsule < 6 mL

Bacterial Retention

• Lot samples retain a minimum of 10⁷ cfu/cm² of B. diminuta per modified ASTM F838, current revision

Endotoxin Level

• < 0.25 EU/mL using Limulus Amoebocyte Lysate (LAL) test

Biological Safety

• Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88>

Sterilization

• Sterilized by gamma irradiation and individually packaged
• AcroPak 20 filters can withstand one autoclave cycle at 131 °C (268 ºF) for 30 min

Part Number	Description	Pkg	Price	Qty
AcroPak 20 Filters with Fluorodyne II Membrane, with Filling Bell
12209	0.1 µm, gamma-irradiated	3/pkg	51.43
12208	0.1 µm, non-sterile	3/pkg	48.71
12201	0.2 µm, gamma-irradiated	3/pkg	50.43
12200	0.2 µm, non-sterile	3/pkg	44.22
AcroPak 200 Capsule with Fluorodyne II Membrane, with Filling Bell
12069	0.2 µm, gamma-irradiated	3/pkg	196.79

Contact Customer Service at 800-521-1520 for possible lead-time and ship date.