SolVac® Filter Holder
Magnetic filter holder simplifies clean-up and degassing of mobile phase solvents and other solutions
- Versatile design fits most HPLC bottles, flasks, and containers, and eliminates the added steps of washing flasks and transferring mobile phase solvent from flask to reservoir.
- Draws directly from HPLC solvent bottle. Less likely to spill aggressive solvents than glass funnels or disposable cups.
- Durable plastic construction is less likely to break than glass funnels, assemblies, or adapters.
- Patented magnetic seal is reliable and leak proof. Eliminates the possibility of membrane shifting or tearing which can occur with aluminum clamps or threaded holders.
- Reusable, chemically resistant polypropylene construction is resistant to common HPLC mobile phase solvents such as methanol, acetonitrile, and tetrahydrofuran.
- Remove contaminating particulate from mobile phase or other solutions
- De-gas mobile phase solvents and solutions
- Eliminate pour-and-wait filtration
- Remove microbial growth every 24 hours from aqueous buffer mobile phases
Materials of Construction
Upper Housing, Housing Base: PolypropyleneFeedline Tubing: Ultra chemical-resistant Tygon*, 4.8 mm (3/16 in.) ID
Thumb Clamp: Celcon*
Feedline Sinker: PTFE
Vacuum Port Adapter, Membrane Seal Gasket, and Seal Gasket: Polyethylene
Effective Filtration Area
10.2 cm2Filter Size
Accepts 47 mm filterInlet/Outlet Connections
Tapered inlet accepts 3.2-6.4 mm (1/8-1/4 in.) ID tubing; outlet seals to bottles with openings 17.8 mm (0.7 in.) ID to 48.3 mm (1.9 in.) ODVacuum Port Adapter
4.8-7.9 mm (3/16 - 5/16 in.) tapered hose barbMaximum Vacuum
63.5 cm Hg (25 in. Hg)Operating Temperature
Ambient; not to exceed 38° C (100° F); not autoclavableChemical Compatibility
For detailed information about chemical compatibility by membrane type, see the Chemical Compatibility Chart on pages 290 - 291.- Place base on the receiving vessel with gasket seal seated on the rim of the vessel.* Then, place the membrane on the clean, dry filter support.

- Attach inlet feedline tubing to the tapered inlet on the upper housing. Place upper housing onto housing base to securely seal the membrane.
- While holding filter housing assembly on receiving vessel, attach vacuum tubing from vacuum source to the vacuum port adapter located on the side of the housing base.

- Place vacuum feedline into solvent to be filtered. Be sure sinker is located well below the surface of the solvent, preferably on the bottom of the vessel. Place the thumb clamp just above the solvent bottle and close it.

- Apply vacuum while holding the SolVac filter housing, applying even pressure to both sides, onto the receiving vessel until full vacuum is drawn. When the required vacuum is achieved and the system is "charged", open the thumb clamp to start the filtration. Continue to filter until all of the solvent is drawn through or the receiving vessel is full.
* Always use a safety-coated receiving vessel that is < 4 L and rated for vacuum applications. Failure to do so may result in implosion of the receiving vessel and potential injury to the user.
HPLC Mobile Phase Filtration Membranes| Membrane | Mobile Phase Application | Technical Information |
| TF (PTFE) | Recommended for use with all organic liquids | Page 212 |
| GH Polypro (GHP, polypropylene) | Recommended for use with organics and aqueous liquids |
Page 203 |
| Nylaflo™ (Nylon) | Not recommended for use with acidic solutions | Page 211 |
| FP Vericel™ (PVDF | Not recommended for use with basic solutions | Page 202 |
| Supor® (PES) | Not recommended for use with keytones | Page 214 |
- Always begin filtration using a dry membrane and a clean dry support base to prevent airlock which can decrease or prevent liquid flow.
PTFE and Supported Membranes. Certain membranes such as supported membranes and fibrous media (e.g. PTFE and glass fiber) may not seal well in the SolVac filter holder due to the rigidity of the membrane or media surface. This may result in reduced flow rate. To correct this occurrence, place a membrane seal gasket on top of the membrane prior to final assembly of the filter holder.Make sure that you save these gaskets once you are done with your filtration so that you can use them in the future.
Hydrophilic Membranes. Once hydrophilic membranes are wetted with an aqueous fluid they do not allow air to pass through them. Because of this, it is critical that the PTFE sinker is on the bottom of the reservoir you are filtering from to minimize the potential to draw air into the filter holder prior to completing filtration.
- Always be sure sinker and feedline remain below the surface of the solvent to prevent air from getting into the feedline and creating an airlock.
- Use a receiving vessel that is of equal or greater volume than the vessel containing the mobile phase solvent to be filtered. Always monitor the filtration process to prevent overflow.
- For optimum performance use vacuum pressure of 51-64 cm (20-25 in.)
- Conventional lab vacuum pumps such as Pall Life Sciences' vacuum pumps (115 and 230 V) are ideal for use with the SolVac filter holder. We recommend the use of a Vacushield™ vent device to protect valves and pump components from damage.
- AcroVent® Device
- Acro® 37 TF Vent Device
- Acro® 50 Vent Devices
- Acro® 50 Vent Filter with Emflon® II Membrane
- Analytical Paper Filters
- Bacterial Air Vent
- DM Metricel® Membrane Disc Filters
- FP Vericel™ (PVDF) Membrane Disc Filters
- GH Polypro (GHP) Membrane Disc Filters
- GLA-5000 Membrane Disc Filters
- GN-4 Metricel® Membrane Disc Filters
- GN-6 Metricel® Membrane Disc Filters
- Glass Fiber Filters
- HT Tuffryn® Membrane Disc Filters
- Ion Exchange Membrane Disc Filters
- Metricel® Black Membrane Disc Filters
- Metricel® Polypropylene Membrane Disc Filters
- Nylaflo™ Membrane Disc Filters
- Nylasorb™ Membrane Disc Filters
- PTFE Membrane Disc Filters
- Pallflex® Filters
- Polypropylene Separators Depth Filters
- Stainless Steel Forceps
- Supor® Membrane Disc Filters
- TCLP Glass Fiber Filters
- Vacushield™ Vent Device
- Vacuum/Pressure Pumps
- Versapor® Membrane Disc Filters
Contact Customer Service at 800-521-1520 for possible lead-time and ship date.
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| *US List Price applies only to products delivered within the US. These prices do not reflect duties, taxes or tariffs, which may apply to purchases made outside of the US. See our General Limited Warranty. |

