AcroPak™ 20 Filters with Supor® Membrane

Efficient Processing of Liquid
Volumes Up To 2 L

• Supor membrane has high flow rates and throughputs, and is ideal for solutions where low protein binding is required. Not recommended for use with some ketones.
• Efficiently processes up to 2 L of chemical and biological fluids.
• Sterilization by gamma irradiation eliminates potential contamination by EtO residuals.
• Upstream vent prevents vapor lock.
• Built-in prefilter extends filter life when particulate-laden solutions such as serum-containing media are processed.

• Designed to add convenience to small- and medium-volume filtration (sterile and non-sterile)
• Suitable for use with fluids containing dilute proteins, preservatives, or other critical components
• Sterile filtration of media and buffers

Materials of Construction

• Filter Media: Supor [hydrophilic polyethersulfone (PES)] membrane
• Housing, Vent Plug: Polypropylene
• Sealing Technology: Thermal bonding
• Filling Bell: Polycarbonate

Pore Size

• 0.8/0.2 μm

Effective Filtration Area

• 20 cm²

Dimensions

• Housing Length: 8.3 cm (3.3 in.)
• Housing Diameter: 6.7 cm (2.7 in.)

Inlet/Outlet Connections

• 6.4 - 12.7 mm (1/4 - 1/2 in.) diameter stepped hose barb with female luer slip interior and filling bell outlet

Typical Hold-Up Volume

• < 2.5 mL

Maximum Operating Temperature and Pressure

• 60 °C (140 °F) at 1.0 bar (100 kPa, 15 psi)
• 4.1 bar (410 kPa, 60 psi) at 21 - 24 °C (70 - 75 °F)

Recommended Integrity Test Minimum Bubble Point - Water

• 3.5 bar (350 kPa, 51 psi)

Typical Water Flow Rate

• mL/min at 0.1 bar (10 kPa): 40 mL/min/psi: 28

Bacterial Retention

• Lot samples retain a minimum of 10⁷ cfu/cm² of B. diminuta per modified ASTM F838, current revision

Endotoxin Level

• < 0.25 EU/mL using Limulus Amoebocyte Lysate (LAL) test

Biological Safety

• Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88>

Sterilization

• Can withstand one autoclave cycle at 125 ºC (257 ºF) for 60 minutes; water wet capsule prior to autoclaving
• PN 12203 is sterilized by gamma irradiation and individually packaged

• Acrodisc® Syringe Filters with Supor® Membrane
• AcroCap™ Positive Pressure Devices
• VacuCap® Vacuum Filtration Devices
• AcroPak™ 200 Capsules with Supor® Membranes
• AcroPak™ 200, 1000 and 1500 Capsules with Supor® Membranes
• Supor® Membrane Disc Filters

Part Number	Description	Pkg	Price	Qty
AcroPak 20 Filters with Supor Membrane
12202	0.8/0.2 µm, non-sterile, with filling bell	3/pkg	44.22
12203	0.8/0.2 µm, gamma-irradiated, with filling bell	3/pkg	50.43

Contact Customer Service at 800-521-1520 for possible lead-time and ship date.