Acrodisc® Syringe Filters with GHP Membrane

The "Universal" Membrane Filter for
All of Your Analytical Filtration Requirements

• Acrodisc PSF syringe filters are Zymark* and SOTAX* Automation Certified to ensure smooth operation and worry-free performance 24 hours a day in automated workstations.
• Avoid the expense and inconvenience of keeping a variety of filters on hand. Versatile filter for aqueous and aggressive organic solvent-based solutions.
• Low protein binding membrane gives high recovery of critical proteinaceous samples.
• Accurate analysis. HPLC certified for low levels of UV-absorbing extractables.
• Easy filtration of particulate-laden samples with glass fiber prefilter version.
• 13 mm Acrodisc syringe filter with minispike configuration offers low hold-up and easy filtration into autosampler vials.
• Protects columns and instrumentation from particulate buildup better than other filters

*Registered Trademarks

• Highly recommended for filtering HPLC samples
• Available in 0.2 μm for UHPLC applications
• The Acrodisc PSF GxF syringe filter provides two to four times the throughput of standard prefilter devices for particulate-laden samples
• 25 mm Acrodisc PSF syringe filter is available in robotic-compatible AutoPack™ packaging for SOTAX AT-70 SMART* and CTS and Zymark TPW*, APWs, and MultiDose* dissolution systems

*Registered Trademark

Materials of Construction

• Filter Media: GH Polypro membrane (GHP, hydrophilic polypropylene)
• Housing: Polypropylene
• GxF Prefilter: Binder-free borosilicate glass

Pore Size

• GHP Membrane: 0.2 and 0.45 μm
• Glass Fiber: 1 μm
• GxF Prefilter: 40 - 1 μm

Effective Filtration Area

• 13 mm: 1.0 cm²
• 25 mm PSF: 3.9 cm²

Sample Volume

• 13 mm: < 10 mL
• 25 mm PSF: < 150 mL

Inlet/Outlet Connections

• 13 mm: Female luer lok inlet, minispike outlet
• 25 mm PSF: Female luer lok inlet, male slip luer outlet

Typical Hold-up Volume(with air purge)

• 13 mm: < 14 µL
• 25 mm PSF: < 125 µL
• 25 mm PSF GxF: < 200 µL

Maximum Operating Temperature

• 25 mm PSF: 55 ºC (131 ºF) at 2.1 bar (210 kPa, 30 psi)

Maximum Operating Pressure

• 13 mm: 6.3 bar (630 kPa, 90 psi)
• 25 mm PSF: 4.1 bar (410 kPa, 60 psi) at 21 - 24 ºC (70 - 75 ºF); 2.1 bar (210 kPa, 30 psi) at 55 ºC (131 ºF)

Typical Water Flow Rate

• mL/min at 0.7 bar (70 kPa, 10 psi)
• 13 mm, 0.2 µm: 17
• 13 mm, 0.45 µm: 28
• mL/min at 2.1 bar (210 kPa, 30 psi)
• 25 mm PSF, 0.2 µm: 215    0.45 µm: 300
• 25 mm GxF/PSF, 0.2 µm: 175    0.45 µm: 195

• 47 mm Filter Funnels, Glass
• AcroPrep™ 24 Filtration System
• HPLC Mobile Phase Filtration Membranes
• SolVac® Filter Holder
• Stainless Steel Forceps
• Vacuum/Pressure Pumps

GH Polypro (GHP) Membrane is Extremely Low in Biomolecule Binding

¹²⁵I-labeled BSA (1.6 µg) or ³²P-labeled DNA (500 ng) were diluted to 5 mL in PBS (BSA) or Tris-EDTA (DNA) and filtered through a 13 mm disc of the indicated membrane. Filtration was carried out using a 10 mL syringe at a flow rate of 1.0 mL/min.

Binding was determined by comparing the amount of radioactivity remaining in the membrane (triplicate) to the activity of the starting material by placing the disc or solution directly into scintillation cocktail and counting in a scintillation counter. Biodyne B membrane is designed for biomolecule binding and was used as a positive control.

Part Number	Description	Pkg	Price	Qty
Acrodisc® Syringe Filters with GHP Membrane, 13 mm
4554	0.2 µm, minispike outlet	100/pkg 300/cs	693.99
4567	0.2 µm, minispike outlet	1000/pkg	1,291.25
4556	0.45 µm, minispike outlet	100/pkg 300/cs	693.99
4563	0.45 µm, minispike outlet	1000/pkg	1,291.25
Acrodisc Syringe Filters With GHP Membrane, 25 mm
4564	0.2 µm	50/pkg, 200/cs	645.58
4566	0.2 µm	1000/pkg	1,666.99
4560	0.45 µm	50/pkg, 200/cs	645.58
4562	0.45 µm	1000/pkg	1,666.99
Acrodisc GF Syringe Filters With GHP Membrane, 25 mm
4559	GF/0.45 µm	50/pkg, 200/cs	653.85
4558	GF/0.45 µm	1000/pkg	1,734.28
Acrodisc PSF Syringe Filters with GHP Membrane, 25 mm
AP-4364	0.2 µm, AutoPack™ tubes	25/pkg 200/cs	562.32
AP-4564	0.2 µm	50/pkg 200/cs	587.87
AP-4566	0.2 µm	1000/pkg	1,893.98
AP-4357	0.45 µm, AutoPack tubes	25/pkg 200/cs	562.32
AP-4560	0.45 µm	50/pkg 200/cs	587.87
AP-4562	0.45 µm	1000/pkg	1,893.98
Acrodisc PSF GxF Syringe Filters with GHP Membrane, 25 mm
AP-4305	GxF/0.2 µm, AutoPack tubes	25/pkg 200/cs	637.31
AP-4307	GxF/0.2 µm	50/pkg 200/cs	637.31
AP-4306	GxF/0.2 µm	1000/pkg	2,282.02
AP-4557	GxF/0.45 µm, AutoPack tubes	25/pkg 200/cs	637.31
AP-4559	GxF/0.45 µm	50/pkg 200/cs	637.31
AP-4558	GxF/0.45 µm	1000/pkg	2,282.02

Contact Customer Service at 800-521-1520 for possible lead-time and ship date.