AcroPak™ 500, 1000, & 1500 Capsules with Supor® Membrane

Fast, final filtration and high throughputs for liquid volumes up to 150 liters

• Provides higher throughputs and faster flow rates than similarly-sized competitive devices.
• Ideal for solutions requiring low protein binding. 
• Saves money by increasing throughput with available built-in prefilter.
• 100% integrity testing assures sterile filtrate.
• 0.1 µm Supor membrane version ensures sterile, mycoplasma-free cell culture media.
• Fusion-welded components eliminate the potential for release of extractables from sealing adhesives.
• Sterilization by gamma irradiation eliminates potential contamination by EtO residuals.

• Large-volume media preparation
• Pilot-scale manufacturing
• Liquids requiring prefiltration, such as serum-containing media
• Sterile filtration of buffers
• Point-of-use filtration for laboratory water
• Reduce mycoplasma with the 0.1 µm pore size

 

 

Materials of Construction

Filter Media: Supor membrane (hydrophilic polyethersulfone)
Housing, Vent Plug, and Filter Support: Polypropylene
Sealing Technology: Thermal bonding
Filling Bell: Polycarbonate

Pore Size

0.1/0.1, 0.2/0.2, 0.8/0.2 and 0.8/0.45 µm

Effective Filtration Area

500 Series: 500 cm²
1000 Series: 1000 cm²
1500 Series: 1500 cm²

Dimensions

Diameter: 6.9 cm (2.7 in.)
Overall Length (without Filling Bell):
500 series: 14.5 cm (5.7 in.)
1000 series: 19.3 cm (7.6 in.)
1500 series: 22.9 cm (9.0 in.)

Inlet/Outlet Connections

500 & 1000 Series:
6.4 - 12.7 mm (1/4 - 1/2 in.) stepped hose barb with filling bell on outlet
1500 Series:
12.7 mm (1/2 in.) straight hose barb, no filling bell on outlet

Typical Hold-up Volume(with 10 psi air purge)

500 series: 30 mL
1000 series: 45 mL

Maximum Operating Temperature

60 °C (140 °F) at 2.1 bar (210 kPa, 30 psi)

Maximum Operating Pressure

Continuous: 4.1 bar (410 kPa, 60 psi) at ambient temperature

Recommended Integrity Test
Minimum Bubble Point – Water

0.2 µm: 3.5 bar (350 kPa, 51 psi)
0.45 µm: 1.7 bar (170 kPa, 24 psi)
60% IPA/40% H₂O (v:v)
0.1 µm: 2.4 bar (240 kPa, 35 psi)

Typical Water Flow Rate

Lpm at 0.1 bar (10 kPa)
[Lpm/psi]:

	500 Sereis	1000 Sereis	1500 Series
0.1/0.1 µm	0.2 (0.2)	0.4 (0.3)
0.2/0.2 µm	0.6 (0.4)	1.1 (0.8)	1.6 (1.1)
0.8/0.2 µm	1.1 (0.8)	1.6 (1.1)	2.2 (1.5)
0.8/0.45 µm	1.3 (0.9)	2.5 (1.7)

Bacterial Retention

0.1/0.1 µm capsules: Lot samples retain a minimum of 10⁷ cfu/cm ² of A. laidlawii challenge per modified ASTM F838-83, current revision
0.2 µm capsules: Lot samples retain a minimum of 10⁷ cfu/cm² of B. diminuta per modified ASTM F838-83, current revision

Endotoxin Level

< 0.25 EU/mL using Limulus Amoebocyte Lysate (LAL) test

Biological Safety

Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88>

Sterilization

Sterilized by gamma irradiation. If desired, autoclave once only prior to use at 121 - 123 °C (250 - 253 °F) for a maximum of 20 min.

Total Throughput Recorded for Devices with an EFA of Up to 1000 cm²

Throughput Determined using 3% TSB

Built-in Prefilter Enhances Total Throughput 

Membrane Type: 47 mm Disc
Throughput Determined using 2.5 % TSB

• Acrodisc® Syringe Filters with Supor Membrane
• AcroCap™ Positive Pressure Devices
• VacuCap® & VacuCap PF Sterile Vacuum Filtration Devices
• AcroPak™ 200 Capsules with Supor® Membranes
• Stainless Stell Pressure Vessels

Part Number	Description	Pkg	Price	Qty
AcroPak 500 Capsules with Supor Membrane
12997	0.1/0.1 µm, sterile	1/pkg	102.77
12995	0.2/0.2 µm, sterile	1/pkg	98.44
12991	0.8/0.2 µm, sterile	1/pkg	85.34
12993	0.8/0.45 µm, sterile	1/pkg	84.00
AcroPak 1000 Capsules with Supor Membrane
12999	0.1/0.1 µm, sterile	1/pkg	147.29
12996	0.2/0.2 µm, sterile	1/pkg	133.72
12992	0.8/0.2 µm, sterile	1/pkg	129.98
12994	0.8/0.45 µm, sterile	1/pkg	126.88
AcroPak 1500 Capsules with Supor Membrane
12686	0.2/0.2 µm, sterile	1/pkg	160.69
12675	0.8/0.2 µm, sterile	1/pkg	153.68

Contact Customer Service at 800-521-1520 for possible lead-time and ship date.